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Mar
28
2008

Key to REM sleep behavior may be glycine

There is new promise on the horizon for those who suffer from REM Sleep Behavior Disorder (RBD), according to researchers at the .

RDB, a neurological disorder that causes violent twitches and muscle contractions during rapid eye-movement (REM) sleep, can lead to serious injuries.

, assistant professor at the University of Toronto, discovered that an inhibitory brain chemical called is responsible for actively suppressing muscle twitches in REM sleep.

Deficiency in glycine levels in the brain cells that control muscles (motoneurons) was found to cause the violent muscle contractions that mimic the primary symptom of RBD.

"This study shows the mechanism that suppresses muscles twitches in REM sleep and this will lead to better treatments and potential cures for this disorder," says Peever.

"Treating REM sleep disorder may have much broader implications, since within five to eight years of being diagnosed with this disorder, 60-80 percent of individuals eventually develop ," Peever added.


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Interesting Apnea Statistics
~~ Apnea in United States ~~

As of May 2, 2009 at 9:47 p.m. (-0500) (ET), the U.S. population
was 306,340,710. Sleep researchers estimate approximately seven percent
of the population suffers from obstructive sleep apnea. Using that
estimate, there are potentially 21,443,850 apneics in the U.S.

~~ Apnea around the world ~~

As of May 2, 2009 at 9:47 p.m. (-0500) (ET), the world population
was 6,777,286,604. Sleep researchers estimate approximately seven percent
of the population suffers from obstructive sleep apnea. Using that
estimate, there are potentially 474,410,062 apneics in the world.