dopamine

Mar
18
2009

Modafinil used to improve cognitive performance affects brain dopamine activity; suggests abuse & dependence potential

Preliminary research in healthy men suggests that the narcolepsy drug modafinil, increasingly being used to enhance cognitive abilities, affects the activity of dopamine in the brain in a way that may create the potential for abuse and dependence, according to a study in JAMA.

Modafinil, a wake-promoting drug used to treat sleep disorders, may enhance cognition and is used off-label for the treatment of cognitive dysfunction in some psychiatric disorders, such as schizophrenia and attention-deficit/hyperactivity disorder (ADHD).


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Aug
23
2008

Sleepless nights increase dopamine in the human brain

Just one night without sleep can increase the amount of the chemical dopamine in the human brain, according to new imaging research in the August 20 issue of the Journal of Neuroscience. Because drugs that increase dopamine, like amphetamines, promote wakefulness, the findings offer a potential mechanism explaining how the brain helps people stay awake despite the urge to sleep.

However, the study also shows that the increase in dopamine cannot compensate for the cognitive deficits caused by sleep deprivation.


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Interesting Apnea Statistics
~~ Apnea in United States ~~

As of May 2, 2009 at 9:47 p.m. (-0500) (ET), the U.S. population
was 306,340,710. Sleep researchers estimate approximately seven percent
of the population suffers from obstructive sleep apnea. Using that
estimate, there are potentially 21,443,850 apneics in the U.S.

~~ Apnea around the world ~~

As of May 2, 2009 at 9:47 p.m. (-0500) (ET), the world population
was 6,777,286,604. Sleep researchers estimate approximately seven percent
of the population suffers from obstructive sleep apnea. Using that
estimate, there are potentially 474,410,062 apneics in the world.