A new study shows that a sleep disorder may be a sign of dementia or Parkinson’s disease up to 50 years before the disorders are diagnosed. The research was published in the July 28, 2010, online issue of Neurology, the journal of the American Academy of Neurology. Using Mayo Clinic records, researchers identified 27 people [...]
Cephalon announced that Mayo Clinic Proceedings published data from a Phase III trial of Nuvigil (armodafinil) Tablets [C-IV] demonstrating it significantly improved wakefulness throughout the shift in patients with excessive sleepiness associated with shift work disorder.
A recently published study that is the first to assess the effectiveness of treating sleep disorders in adults with a traumatic brain injury (TBI) shows treatment may result in the objective resolution of the sleep disorder without improvements in daytime sleepiness or neuropsychological function.
Results show that in brain-injured subjects with obstructive sleep apnea, three months of treatment with CPAP therapy dramatically reduced the severity of OSA from 31.4 to 3.8 apneas and hypopneas per hour of sleep; however, there was no demonstrable improvement in measures of daytime sleepiness.
Preliminary research in healthy men suggests that the narcolepsy drug modafinil, increasingly being used to enhance cognitive abilities, affects the activity of dopamine in the brain in a way that may create the potential for abuse and dependence, according to a study in JAMA.
Modafinil, a wake-promoting drug used to treat sleep disorders, may enhance cognition and is used off-label for the treatment of cognitive dysfunction in some psychiatric disorders, such as schizophrenia and attention-deficit/hyperactivity disorder (ADHD).
In healthy people, both sleepiness and vigilance show a relationship with core body temperature and skin temperature. When core body temperature is high during the daytime, skin temperature is low, which translates into optimal vigilance.
Researchers noted during a recent study, though, that when core body temperature is low at night time, skin temperature is high, which correlates to optimal sleep. Among those suffering from narcolepsy, however, direct manipulations of their skin and core body temperatures affect their vigilance and sleepiness.
Epidemiologic surveys suggest that mean sleep duration among U.S. adults has decreased during the past two decades (CDC, unpublished data, 2007). An estimated 50–70 million persons in the United States have chronic sleep and wakefulness disorder.
The majority of patients with narcolepsy/cataplexy experience a number of symptoms of eating disorders, with an irresistible craving for food and binge eating as the most prominent features, according to a study published in the March 1 issue of the journal Sleep.
Study authors Hal Droogleever Fortuyn, M.D., and Sebastiaan Overeem, M.D., of the Radboud University Nijmegen Medical Center in The Netherlands, focused on 60 patients who had been diagnosed with narcolepsy with cataplexy (N/C) who were recruited from specialized sleep centers and 120 healthy controls.
Learn about sleep’s connection with mood, health, alertness, and performance in the workplace as well as sleep problems such as insomnia, snoring, sleep apnea, restless legs syndrome, narcolepsy, and excessive daytime sleepiness.
Vanda, Pharmaceuticals, Proof-of-Concept, Phase II, clinical testing, VSF-173, excessive sleepiness, maintenance of wakefulness tests, MWT, modafinil, Provigil, Nuvigil, narcolepsy, polysomnography, PSG, Mihael Polymeropoulos, shift work sleep disorder, neuro-degenerative disorders, sleep disorders, sleepiness, excessive sleepiness, problem sleepiness.
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As of May 2, 2009 at 9:47 p.m. (-0500) (ET), the U.S. population
was 306,340,710. Sleep researchers estimate approximately seven percent
of the population suffers from obstructive sleep apnea. Using that
estimate, there are potentially 21,443,850 apneics in the U.S.
~~ Apnea around the world ~~
As of May 2, 2009 at 9:47 p.m. (-0500) (ET), the world population
was 6,777,286,604. Sleep researchers estimate approximately seven percent
of the population suffers from obstructive sleep apnea. Using that
estimate, there are potentially 474,410,062 apneics in the world.
